diff --git a/shell/browser/ui/autofill_popup.cc b/shell/browser/ui/autofill_popup.cc
index 2c266f8427..2640425fdf 100644
--- a/shell/browser/ui/autofill_popup.cc
+++ b/shell/browser/ui/autofill_popup.cc
@@ -172,20 +172,30 @@ void AutofillPopup::CreateView(content::RenderFrameHost* frame_host,
                                bool offscreen,
                                views::View* parent,
                                const gfx::RectF& r) {
+  DCHECK(parent);
+
   Hide();
 
+  // A Widget can outlive its NativeWidget during teardown.
+  // Do not create a child popup once the parent native view is gone.
+  views::Widget* parent_widget = parent->GetWidget();
+  if (!parent_widget || parent_widget->IsClosed() ||
+      !parent_widget->GetNativeView()) {
+    return;
+  }
+
   frame_host_ = frame_host;
   element_bounds_ = gfx::ToEnclosedRect(r);
 
-  gfx::Vector2d height_offset(0, element_bounds_.height());
-  gfx::Point menu_position(element_bounds_.origin() + height_offset);
+  gfx::Vector2d height_offset{0, element_bounds_.height()};
+  gfx::Point menu_position{element_bounds_.origin() + height_offset};
   views::View::ConvertPointToScreen(parent, &menu_position);
-  popup_bounds_ = gfx::Rect(menu_position, element_bounds_.size());
+  popup_bounds_ = gfx::Rect{menu_position, element_bounds_.size()};
 
   parent_ = parent;
   parent_->AddObserver(this);
 
-  view_ = new AutofillPopupView(this, parent->GetWidget());
+  view_ = new AutofillPopupView{this, parent_widget};
 
   if (offscreen) {
     auto* rwhv = embedder_frame_host ? embedder_frame_host->GetView()
@@ -212,13 +222,19 @@ void AutofillPopup::Hide() {
 
 void AutofillPopup::SetItems(const std::vector<std::u16string>& values,
                              const std::vector<std::u16string>& labels) {
-  DCHECK(view_);
   values_ = values;
   labels_ = labels;
+
+  if (!view_)
+    return;
+
   UpdatePopupBounds();
   view_->OnSuggestionsChanged();
-  if (view_)  // could be hidden after the change
-    view_->DoUpdateBoundsAndRedrawPopup();
+
+  if (!view_)
+    return;
+
+  view_->DoUpdateBoundsAndRedrawPopup();
 }
 
 void AutofillPopup::AcceptSuggestion(int index) {
diff --git a/shell/browser/ui/views/autofill_popup_view.cc b/shell/browser/ui/views/autofill_popup_view.cc
index 630c22dbcb..f61f873730 100644
--- a/shell/browser/ui/views/autofill_popup_view.cc
+++ b/shell/browser/ui/views/autofill_popup_view.cc
@@ -69,9 +69,16 @@ AutofillPopupView::~AutofillPopupView() {
 void AutofillPopupView::Show() {
   if (!popup_)
     return;
-  bool visible = parent_widget_->IsVisible();
-  visible = visible || view_proxy_;
-  if (!visible || parent_widget_->IsClosed())
+
+  DCHECK(parent_widget_);
+
+  // The parent Widget can outlive its NativeWidget during teardown.
+  // Don't initialize the popup after the native parent view is gone.
+  if (parent_widget_->IsClosed() || !parent_widget_->GetNativeView())
+    return;
+
+  const bool visible = view_proxy_ || parent_widget_->IsVisible();
+  if (!visible)
     return;
 
   const bool initialize_widget = !GetWidget();
@@ -234,10 +241,14 @@ void AutofillPopupView::DoUpdateBoundsAndRedrawPopup() {
   if (!popup_)
     return;
 
+  views::Widget* const widget = GetWidget();
+  if (!widget)
+    return;
+
   // Clamp popup_bounds_ to ensure it's never zero-width.
   popup_->popup_bounds_.Union(
       gfx::Rect(popup_->popup_bounds_.origin(), gfx::Size(1, 1)));
-  GetWidget()->SetBounds(popup_->popup_bounds_);
+  widget->SetBounds(popup_->popup_bounds_);
   if (view_proxy_.get()) {
     view_proxy_->SetBounds(popup_->popup_bounds_in_view());
   }