diff --git a/packages/react-fast-refresh/client.js b/packages/react-fast-refresh/client.js
index e5aa825bb2..e04feedf7c 100644
--- a/packages/react-fast-refresh/client.js
+++ b/packages/react-fast-refresh/client.js
@@ -16,9 +16,18 @@ if (
   hmrEnabled &&
   enabled
 ) {
+  let inBefore = false;
   module.hot.onRequire({
     before(module) {
+      if (inBefore) {
+        // This is a module required while loading the react refresh runtime
+        // Do not initialize it to avoid an infinite loop 
+        return;
+      }
+
+      inBefore = true;
       init(module);
+      inBefore = false;
     }
   });